* This data for Bis(2-ethylhexyl)Phthalate and Vinyl Chloride Monomer apply to the pure form of the compound. Updated 2011. However, in a case-control study on testicular cancer and various occupational exposures, we observed a 6-fold increase in the risk for testicular cancer, mainly seminoma, among men exposed to polyvinyl chloride (PVC) plastics.6,7 Vinyl chlo- Vinyl chloride exists in liquid form if it is kept under high pressure or at low temperatures (less than -13.4�C). EPA has classified vinyl chloride as a Group A, human carcinogen. Vinyl chloride is an organochloride with the formula H 2 C=CHCl that is also called vinyl chloride monomer (VCM) or chloroethene.This colorless compound is an important industrial chemical chiefly used to produce the polymer polyvinyl chloride (PVC). OEHHA 2009. Please visit topics related to environmental health, safety, and toxicology on MedlinePlus, the NLM’s flagship website for health information for patients, families, and the general public.. Breathing vinyl chloride for long periods of time can result in permanent liver damage, immune reactions, nerve damage, and liver cancer. Vinyl chloride is used to make polyvinyl chloride (PVC). PVC (polyvinyl chloride), a synthetic resin made from the polymerization of vinyl chloride. ; There are over 200 types of cancer. Exposure to polyvinyl chloride dust was associated with an increased incidence of lung tumours in one study; the authors suggested that trapped vinyl chloride monomer was responsible [ref: 30]. Glioblastoma multiforme accounts for 50 percent of gliomas, according to the University of Connecticut. Cancer is a major concern from exposure to vinyl chloride via inhalation, as vinyl chloride exposure has been shown to increase the risk of a rare form of liver cancer in humans. Polyvinyl chloride (PVC) is a widely used building material praised for its durability, yet criticized for its potential health hazards. No relation was found between lung cancer and cumulative VCM exposure. (Polyvinyl Chloride contains less than 1% by weight)** Vinyl Chloride Monomer is an OSHA cancer suspect agent, ACGIH confirmed human carcinogen, and NTP and IARC human carcinogen. CANCER-SUSPECT AGENT IN THIS AREA. Polyvinyl chloride (PVC) is one of the most commonly manufactured plastics in the world, used in a wide variety of products including packaging, pipes, automotive parts, construction materials and furniture. It is also known as chloroethene, chloroethylene, ethylene monochloride, or monochloroethylene. Polyvinyl chloride, also known as PVC or vinyl, is a synthetic resin produced from the polymerization of vinyl chloride.It is an odorless and solid plastic and can come in the form of white powder or pellets. Vinyl chloride is a colorless gas at normal temperatures. Incidence of cancer among workers exposed to vinyl chloride in polyvinyl chloride manufacture. Breathing high levels of vinyl chloride for short periods of time can cause dizziness, sleepiness, unconsciousness, and at extremely high levels can cause death. It is in such widespread usage due to its strength and resistance to sunlight, oil and chemicals, weathering and fire. [Note: Shipped as a liquefied compressed gas.] POLYVINYL CHLORIDE LATEX may become discolored may on exposure to heat or light in the absence of stabilizers (NTP, 1992). Results: In PVC baggers exposed to high levels of respirable PVC particles in the workplace, the lung cancer OR increases by 20% for each extra year of work (OR = 1.2003; 95% CI 1.0772 to 1.3469; p = 0.0010), when the influence of age and smoking habits is controlled. Development of oral cancer tissue-mimicking phantom based on polyvinyl chloride plastisol and graphite for terahertz frequencies Tianmiao Zhang , a, b, * Ravshanjon Nazarov , a Alexey P. Popov , c Petr S. Demchenko , a Alexander V. Bykov , c Roman O. Grigorev , a Anna V. Kuzikova , a Victoria Y. Soboleva , a Dmitry V. Zykov , a Igor V. Meglinski , c, d, e and Mikhail K. Khodzitskiy a MMWR 1974;23:49-50 (February 9, 1974) Between September 1967 and December 1973, 4 cases of angiosarcoma of the liver were diagnosed among men employed in the polyvinyl chloride polymerization section of a B.F. Goodrich plant near Louisville, Kentucky. Angiosarcoma of the Liver Among Polyvinyl Chloride Workers -- Kentucky. It is flammable (burns easily) as a gas and is not stable at high temperatures. Public Notices Related to this Chemical. We talked to the PVC Guru to get all the answers every parent should know. Two of Polyvinyl Chloride s impurities are listed as carcinogens. Most often used in construction, PVC is a plastic composed of three elements: carbon, hydrogen and chlorine. The Tox Town website was discontinued as of October 1, 2020. Uses [of PolyVinyl Chloride] The results of a follow up study of the incidence of cancer and the mortality in a cohort of 454 male workers producing vinyl chloride and polyvinyl chloride are presented. The National Institute of Environmental Health Sciences (NIEHS) also offers related resources that may be of interest: Air Resources Board; The vinyl chloride monomer is a suspected carcinogen. Chloroethene, Chloroethylene, Ethylene monochloride, Monochloroethene, Monochloroethylene, VC, VCM, Vinyl chloride monomer (VCM) Colorless gas or liquid (below 7°F) with a pleasant odor at high concentrations. As a building material, PVC is cheap, durable, and easy to assemble. Author information: (1)National Hospital, Center for Occupational and Environmental Medicine, Oslo, Norway. 2008 law banning phthalates from children's toys does not cover the PVC in school supplies. PVC is very corrosive and abrasive and cutters that are not made from stainless steel or a comparably corrosive resistant material are likely to deteriorate over time. Occupational exposures were assessed in a case‐control study on testicular cancer using self‐administered questionnaires. Polyvinyl chloride, better known as PVC or vinyl, is an inexpensive plastic so versatile it has become completely pervasive in modern society.The list of products made from PVC is exhaustive, ranging from phonograph records to drainage and potable piping, water bottles, cling film, credit cards and toys. Exposure to vinyl chloride occurs mainly in the workplace. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. ... Manufacturers use vinyl chloride to produce polyvinyl chloride, or PVC. Polyvinyl chloride – also known as PVC or vinyl – has become an intrinsic part of our lives ever since the early-mid 20th century. One type of brain cancer is glioblastoma multiforme, a grade IV astroyctoma. Melanoma occurred in excess in one study [ref: 12] but has not been mentioned in others. In addition to reports that pertained to these cohorts in their entirety, several studies reported findings from individual Around the world, over 50% of PVC manufactured is used in construction. Learn more about PVC in this article. Unfortunately, PVC can also harm people's health. Studies have linked several health problems, including liver cancer… About … Cancer in Humans Vinyl chloride was evaluated in previous IARC Monographs (IARC, 1979 , 1987 2008) and ... polyvinyl chloride or poly-vinyl chloride products. In Polyvinyl Chloride Bis(2-ethylhexyl)Phathalate exist … Testicular cancer has usually not been regarded to be an occu-pational disease. CNC Machining: Polyvinyl Chloride can be cut on a CNC machine but any machinist who has tried has probably experienced degradation in the cutter depending on the material it is made from. Work ers employed in PVC plants are at high risk with respect to PVC-induced lung disease. Polyvinyl chloride, or PVC, is a major source of phthalates – which are the same dangerous plastic softeners banned from children's toys last year. Personal Risks. Polyvinyl chloride, (IUPAC Polychloroethene) commonly abbreviated PVC, is a widely used thermoplastic polymer. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. PVC was discovered accidentally in the early 19 th century when the polymer appeared as a white solid inside sunlight-exposed flasks of vinyl chloride. Polyvinyl chloride is more often referred to by its less-technical names, PVC and vinyl. PVC is used in an enormous range of domestic and industrial products, from raincoats and shower curtains to window frames and indoor plumbing. Langård S(1), Rosenberg J, Andersen A, Heldaas SS. ; Anything that may cause a normal body cell to develop abnormally potentially can cause cancer; general categories of cancer-related or causative agents are as follows: chemical or toxic compound exposures, ionizing radiation, some pathogens, and human genetics. Belongs to the Following … Next to polyethylene, it is the most widely used plastic in the world. * Bis(2-ethylhexyl)Phthalate is a NTP anticipated human carcinogen and IARC possible human carcinogen. Cancer is the uncontrolled growth of abnormal cells anywhere in a body. In addition to the other requirements in this paragraph (l), the employer shall ensure that labels for containers of polyvinyl chloride resin waste from reactors or other waste contaminated with vinyl chloride are legible and include the following information: In total, answers were obtained … Monomer* is an OSHA cancer suspect agent, ACGIH confirmed human carcinogen, and NTP and IARC human carcinogen. It has both industrial and household uses. Proposition 65 NSRLs and MADLs Aug 15, 2013. Vinyl chloride, a chemical known to cause cancer, poisons the air breathed by workers and people living in contaminated communities. In terms of revenue generated, it is one of the most valuable products of the chemical industry. If degraded, can transfer plasticizers, some of which are toxic. PVC, or Polyvinyl Chloride, is a type of plastic used in millions of everyday items such as pipes, toys, carpet backing, bottles and credit cards. 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